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Objective To investigate the detection rates and types of hemoglobinopathy in Xiaolan district of Zhongshan city to provide the basis for prepotency .Methods 7 652 pregnant women with pregnancy detection in our hospital from June 2010 to De‐cember 2013 were selected and performed the electrophoresis by the Hydrasys automatic hemoglobin electrophoresis system .The hemoglobin components were scanned out and performed the statistical analysis .Results Among 7 652 samples ,1 057 cases of sus‐pected hemoglobinopathy were screened out with the detection rate of 10 .36% .Among them ,511 cases(6 .68% ) were Hb A2 3 .5% (suspected β‐thalassemia) ,the detection rate of Hb A2 >3 .5% was lower than that of Hb A2 < 2 .0% ,the difference had statistical significance(P< 0 .05) .11 cases (0 .14% ) were Hb C or E ,9 cases (0 .12% ) were Hb J or K ,8 cases (0 .10% ) were Hb H ,7 cases (0 .09% ) were Hb Bart′s ,1 case was Hb CS ,2 cases were Hb G and 1 case was Hb D ,which accounted for 0 .04% .Conclusion Hemoglobin electrophoresis can screen hemoglobinopa‐thy effectively .The hemoglobinopathy screening in this area should be conducted as soon as possible ,which has an important signif‐icance to prepotency .
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Objective To evaluate the preliminary screening value of bacterium(BACT),leukocyte count(WBC)detected by the UF-1000i urine sediment analyzer and nitrite(NIT)and leukocyte esterase(LEU)detected by the urine dry chemical dipstick analy-zer in diagnosing urinary tract infection(UTI).Methods A total of 346 inpatients or outpatients with suspected UTI in our hospital from July 2012 to June 2013 were performed the midstream urine culture.Among them,91 positive cases as the experimental group and 255 negative cases as the control group were simultaneously performed the urine dry chemical analysis and the urinary sediment analysis.The performance of the various indexes in screening UTI was evaluated with the bacterial culture results as the golden standard.Results The positive rates of NIT,LEU,WBC,BACT,NIT+LEU and WBC+BACT in the experimental group were significantly higher than those in the control group with the statistical differences between the two groups(P <0.05).The areas un-der the ROC curve for diagnosing UTI in NIT,LEU,WBC,BACT,NIT+LEU and WBC+BACT were 0.602,0.664,0.715, 0.770,0.713 and 0.760 respectively,95%CI was 0.530-0.675,0.603-0.725,0.655 -0.775,0.716 -0.824,0.651 -0.774 and 0.704-0.817 respectively;their sensitivity for diagnosing UTI was 0.26,0.86,0.79,0.74,0.86 and 0.85 respectively;The speci-ficity was 0.94,0.47,0.47,0.51,0.46 and 0.33 respectively;The positive likelihood ratio was 4.48,1.62,1.51,1.49,1.58 and 1.27 respectively;The negative likelihood ratio was 0.78,0.30,0.44,0.52,0.31 and 0.46 respectively;The positive predictive value was 0.62, 0.37,0.35,0.35,0.36 and 0.31 respectively;The negative predictive value was 0.78,0.90,0.86,0.84,0.90 and 0.86 respectively.Conclu-sion In the rapid screening of UTI,the indexes of NIT,LEU,WBC and BACT all have the higher negative predictive values.
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Objective To investigate the epidemic characteristics of hyperuricemia (HUA) in physical examination adults of Xia‐olan region .Methods 28 659 cases of physical examination adults were selected as research subjects in 2011-2012 .The levels of u‐rine acid were detected and the HUA positive rates were statistically analyzed .Results The positive rate of HUA during 2012 (27 .4% ) was lower than that during 2011 (35 .6% ) ,and the differences was statically significant(P<0 .01) .The positive rate of HUA in men was significantly higher than that in women(P<0 .05) .61 -94 age group had the highest HUA positive rate .The third quarter (July to September) was the the high‐frequency time of HUA in a year .Conclusion Grasping the epidemiological characteristics of HUA is conducive to disease prevention .